{"id":6096,"date":"2026-03-23T11:36:11","date_gmt":"2026-03-23T16:36:11","guid":{"rendered":"https:\/\/www.cooking2thrive.com\/blog\/?p=6096"},"modified":"2026-03-23T11:36:13","modified_gmt":"2026-03-23T16:36:13","slug":"medical-treatment-of-celiac-disease","status":"publish","type":"post","link":"https:\/\/www.cooking2thrive.com\/blog\/medical-treatment-of-celiac-disease\/","title":{"rendered":"Medical Treatment of Celiac Disease"},"content":{"rendered":"\n<p>In 2018, I asked whether you\u2019d be an early adopter of medical treatment of celiac disease.<\/p>\n\n\n\n<figure class=\"wp-block-embed is-type-wp-embed is-provider-in-thriver-words wp-block-embed-in-thriver-words\"><div class=\"wp-block-embed__wrapper\">\n<blockquote class=\"wp-embedded-content\" data-secret=\"FzmfNI9yF6\"><a href=\"https:\/\/www.cooking2thrive.com\/blog\/looking-down-the-road-at-potential-celiac-disease-treatment-will-you-be-an-early-adopter\/\">Looking Down the Road at Potential Celiac Disease Treatment, Will You be an Early Adopter?<\/a><\/blockquote><iframe class=\"wp-embedded-content\" sandbox=\"allow-scripts\" security=\"restricted\" style=\"position: absolute; clip: rect(1px, 1px, 1px, 1px);\" title=\"&#8220;Looking Down the Road at Potential Celiac Disease Treatment, Will You be an Early Adopter?&#8221; &#8212; in thriver words\" src=\"https:\/\/www.cooking2thrive.com\/blog\/looking-down-the-road-at-potential-celiac-disease-treatment-will-you-be-an-early-adopter\/embed\/#?secret=hkiik5qNfW#?secret=FzmfNI9yF6\" data-secret=\"FzmfNI9yF6\" width=\"600\" height=\"338\" frameborder=\"0\" marginwidth=\"0\" marginheight=\"0\" scrolling=\"no\"><\/iframe>\n<\/div><\/figure>\n\n\n\n<p>When a friend recently assumed I\u2019d give my kids a pill rather than restrict them to a gluten-free diet, I was surprised.<\/p>\n\n\n\n<p>When there\u2019s a way to address symptoms caused by a disease or condition through dietary changes without it resulting in life-threatening results, that is the choice I\u2019ll make. Could that change? Perhaps. I\u2019m always open to advancing science. If there were a vaccine for Celiac Disease that had been thoroughly tested, I would still be extra cautious when it comes to developing children because <strong>they can live a healthy life without medication<\/strong>.<\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large\"><img decoding=\"async\" loading=\"lazy\" width=\"675\" height=\"450\" src=\"https:\/\/www.cooking2thrive.com\/blog\/c2tblog-content\/uploads\/2026\/03\/pills-675x450.jpg\" alt=\"assorted shapes and colors of pills\" class=\"wp-image-6097\" srcset=\"https:\/\/www.cooking2thrive.com\/blog\/c2tblog-content\/uploads\/2026\/03\/pills-675x450.jpg 675w, https:\/\/www.cooking2thrive.com\/blog\/c2tblog-content\/uploads\/2026\/03\/pills-338x225.jpg 338w, https:\/\/www.cooking2thrive.com\/blog\/c2tblog-content\/uploads\/2026\/03\/pills-768x512.jpg 768w, https:\/\/www.cooking2thrive.com\/blog\/c2tblog-content\/uploads\/2026\/03\/pills-1536x1024.jpg 1536w, https:\/\/www.cooking2thrive.com\/blog\/c2tblog-content\/uploads\/2026\/03\/pills-2048x1365.jpg 2048w, https:\/\/www.cooking2thrive.com\/blog\/c2tblog-content\/uploads\/2026\/03\/pills-1200x800.jpg 1200w\" sizes=\"(max-width: 709px) 85vw, (max-width: 909px) 67vw, (max-width: 984px) 61vw, (max-width: 1362px) 45vw, 600px\" \/><\/figure><\/div>\n\n\n<p>For me, the distinction is in automatically choosing convenience vs committing to a less convenient, but well-established healthy option. If we follow the line of reasoning that convenience rules, there should be no question that fast-food is the best choice for our children. Hopefully, we know better. And hopefully, we are more thoughtfully informed when choosing other options for our kids.<\/p>\n\n\n\n<p><strong>With that in mind, let\u2019s review the status of previously explored treatments:<\/strong><\/p>\n\n\n\n<p><strong>BL-7010<\/strong> has not completed clinical trials evaluating safety. <a href=\"https:\/\/clinicaltrials.gov\/study\/NCT01990885?intr=BL-7010\">https:\/\/clinicaltrials.gov\/study\/NCT01990885?intr=BL-7010<\/a><\/p>\n\n\n\n<p><strong>Egg Yolk Therapy <\/strong>aka dietary supplement <strong>AGY-010<\/strong> completed a study of 149 individuals. That\u2019s too small a number of individuals to draw any conclusion other than further research is needed<\/p>\n\n\n\n<p><a href=\"https:\/\/clinicaltrials.gov\/study\/NCT03707730\">https:\/\/clinicaltrials.gov\/study\/NCT03707730<\/a><\/p>\n\n\n\n<p><strong>Larazotide Acetate<\/strong> entered a Phase 3 clinical trial for safety in 2022. This study was terminated.<\/p>\n\n\n\n<p><strong>Latiglutenase<\/strong><strong> entered Phase 2B clinical trials on an oral dissolvable powder in 2023. &nbsp;A Phase 3 trial is planned.<\/strong><\/p>\n\n\n\n<p><a href=\"https:\/\/adisinsight.springer.com\/trials\/700318623\">https:\/\/adisinsight.springer.com\/trials\/700318623<\/a><\/p>\n\n\n\n<p><strong>Saliva Rothia<\/strong> was studied in 24 children in a clinical trial published in 2024.<\/p>\n\n\n\n<p><a href=\"https:\/\/www.nature.com\/articles\/s41598-024-67677-4\">https:\/\/www.nature.com\/articles\/s41598-024-67677-4<\/a><\/p>\n\n\n\n<p><strong>TIMP-Gliadin<\/strong> was studied in a trial published in 2024.<\/p>\n\n\n\n<p><a href=\"https:\/\/clinicaltrials.gov\/study\/NCT03409796\">https:\/\/clinicaltrials.gov\/study\/NCT03409796<\/a><\/p>\n\n\n\n<p><strong>Nexvax2<\/strong> trials were discontinued when the vaccine proved to be no more effective than placebo.<\/p>\n\n\n\n<p>What we can see from a comparison of the previous list and this one is that it takes a very long time to bring new treatments to market even when early trials are promising. There are many complicating factors like funding, participant recruitment, and world events like pandemics.<\/p>\n\n\n\n<p>This can be frustrating for anyone who has a disease that must be treated with medication! While you may not feel lucky to have celiac disease, at least there\u2019s a dietary alternative.<\/p>\n\n\n\n<p>Researchers continue to explore. For a quick view of the clinical development pipeline for treatment of celiac disease, visit:<\/p>\n\n\n\n<p><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S1359644624002381\">https:\/\/www.sciencedirect.com\/science\/article\/pii\/S1359644624002381<\/a><\/p>\n\n\n\n<p>Eventually, there may be a safe, effective, convenient choice. Until that time, we\u2019re here to help you manage the diet.<\/p>\n\n\n\n<p><em>Disclosure of Material Connection: I have not received any compensation for writing this post. I have no material connection to the brands, products, or services that I have mentioned. I am disclosing this in accordance with the Federal Trade Commission&#8217;s 16 CFR, Part 255: &#8220;Guides Concerning the Use of Endorsements and Testimonials in Advertising<\/em>.&#8221;<\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><img decoding=\"async\" loading=\"lazy\" width=\"600\" height=\"300\" src=\"https:\/\/www.cooking2thrive.com\/blog\/c2tblog-content\/uploads\/2022\/09\/STC_ad_22_OL-8.png\" alt=\"\" class=\"wp-image-4940\" srcset=\"https:\/\/www.cooking2thrive.com\/blog\/c2tblog-content\/uploads\/2022\/09\/STC_ad_22_OL-8.png 600w, https:\/\/www.cooking2thrive.com\/blog\/c2tblog-content\/uploads\/2022\/09\/STC_ad_22_OL-8-350x175.png 350w\" sizes=\"(max-width: 709px) 85vw, (max-width: 909px) 67vw, (max-width: 984px) 61vw, (max-width: 1362px) 45vw, 600px\" \/><\/figure><\/div>","protected":false},"excerpt":{"rendered":"<p>In 2018, I asked whether you\u2019d be an early adopter of medical treatment of celiac disease. When a friend recently assumed I\u2019d give my kids a pill rather than restrict them to a gluten-free diet, I was surprised. When there\u2019s a way to address symptoms caused by a disease or condition through dietary changes without &hellip; <a href=\"https:\/\/www.cooking2thrive.com\/blog\/medical-treatment-of-celiac-disease\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;Medical Treatment of Celiac Disease&#8221;<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[4005,2399,140,4006,2401],"_links":{"self":[{"href":"https:\/\/www.cooking2thrive.com\/blog\/wp-json\/wp\/v2\/posts\/6096"}],"collection":[{"href":"https:\/\/www.cooking2thrive.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.cooking2thrive.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.cooking2thrive.com\/blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.cooking2thrive.com\/blog\/wp-json\/wp\/v2\/comments?post=6096"}],"version-history":[{"count":2,"href":"https:\/\/www.cooking2thrive.com\/blog\/wp-json\/wp\/v2\/posts\/6096\/revisions"}],"predecessor-version":[{"id":6099,"href":"https:\/\/www.cooking2thrive.com\/blog\/wp-json\/wp\/v2\/posts\/6096\/revisions\/6099"}],"wp:attachment":[{"href":"https:\/\/www.cooking2thrive.com\/blog\/wp-json\/wp\/v2\/media?parent=6096"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.cooking2thrive.com\/blog\/wp-json\/wp\/v2\/categories?post=6096"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.cooking2thrive.com\/blog\/wp-json\/wp\/v2\/tags?post=6096"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}