{"id":4737,"date":"2022-03-07T14:59:33","date_gmt":"2022-03-07T20:59:33","guid":{"rendered":"https:\/\/www.cooking2thrive.com\/blog\/?p=4737"},"modified":"2022-03-07T14:59:35","modified_gmt":"2022-03-07T20:59:35","slug":"not-exactly-an-allergy","status":"publish","type":"post","link":"https:\/\/www.cooking2thrive.com\/blog\/not-exactly-an-allergy\/","title":{"rendered":"Not Exactly an Allergy"},"content":{"rendered":"\n<p>Even though your nose is running, your stomach churning, and your skin itching, you may be experiencing something that\u2019s not exactly an allergy. It could be <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7463562\/\" target=\"_blank\" rel=\"noreferrer noopener\" aria-label=\"histamine intolerance (opens in a new tab)\">histamine intolerance<\/a>. <\/p>\n\n\n\n<div class=\"wp-block-image\"><figure class=\"aligncenter size-large\"><img decoding=\"async\" loading=\"lazy\" width=\"490\" height=\"450\" src=\"https:\/\/www.cooking2thrive.com\/blog\/c2tblog-content\/uploads\/2022\/03\/IMG_2054-490x450.jpg\" alt=\"\" class=\"wp-image-4740\" srcset=\"https:\/\/www.cooking2thrive.com\/blog\/c2tblog-content\/uploads\/2022\/03\/IMG_2054-490x450.jpg 490w, https:\/\/www.cooking2thrive.com\/blog\/c2tblog-content\/uploads\/2022\/03\/IMG_2054-245x225.jpg 245w, https:\/\/www.cooking2thrive.com\/blog\/c2tblog-content\/uploads\/2022\/03\/IMG_2054-768x705.jpg 768w, https:\/\/www.cooking2thrive.com\/blog\/c2tblog-content\/uploads\/2022\/03\/IMG_2054-1536x1410.jpg 1536w, https:\/\/www.cooking2thrive.com\/blog\/c2tblog-content\/uploads\/2022\/03\/IMG_2054-1200x1102.jpg 1200w, https:\/\/www.cooking2thrive.com\/blog\/c2tblog-content\/uploads\/2022\/03\/IMG_2054.jpg 1720w\" sizes=\"(max-width: 490px) 85vw, 490px\" \/><\/figure><\/div>\n\n\n\n<p><strong>Histamine Intolerance<\/strong><\/p>\n\n\n\n<p>Histamine intolerance, also known as enteral histaminosis, is a disorder that arises because of a body\u2019s inability to degrade histamine due to diminished diamine oxidase (DAO) enzyme activity which leads to histamine accumulation in plasma and the appearance of adverse effects. That means when a person with histamine intolerance eats foods high in histamines (or that trigger their production) they\u2019ll have an excess of histamine in their system just like they would if an allergic reaction triggered their body to release <a href=\"https:\/\/www.webmd.com\/allergies\/what-are-histamines\" target=\"_blank\" rel=\"noreferrer noopener\" aria-label=\"histamines (opens in a new tab)\">histamines<\/a>. Unsurprisingly, the resulting symptoms are similar. <\/p>\n\n\n\n<p><strong>Symptoms<\/strong><\/p>\n\n\n\n<p>Symptoms of histamine intolerance include headache,\ndizziness, nasal congestion, sneezing, bloating, diarrhea, abdominal pain,\nnausea, itching, swelling, eczema, tachycardia, and hypotonia. The most common\nare gastrointestinal followed by dizziness, headaches, and palpitations, then\nrespiratory and finally, dermatological. An Austrian study found an average of\n11 symptoms per patient. That\u2019s a lot of discomfort.<\/p>\n\n\n\n<p>And while histamine intolerance may be causing a lot of unpleasantness,\nthe lack of consensus for a diagnostic algorithm makes diagnosis a dicey\nproposition. Patients often end up seeing multiple physicians in an effort to\nget a diagnosis and treatment that will reduce symptoms. <\/p>\n\n\n\n<p><strong>Treatment<\/strong><\/p>\n\n\n\n<p>The primary strategy for treating histamine intolerance is to follow a low-histamine diet. <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7463562\/table\/biomolecules-10-01181-t001\/?report=objectonly\" target=\"_blank\" rel=\"noreferrer noopener\" aria-label=\"Foods to avoid (opens in a new tab)\">Foods to avoid<\/a> include spinach, eggplant, tomatoes, fermented foods, and meat or fish that is not fresh. It is also possible for papayas, kiwis, strawberries, pineapples, and plums to trigger the release of histamine so they should be consumed with caution.<\/p>\n\n\n\n<p>DAO supplements have been proposed as an additional\ntreatment. In Europe, regulations authorize a DAO supplement of enteric-coated\nporcine kidney protein extract to be marketed as food for special medical\npurposes. <\/p>\n\n\n\n<p><strong>More to Come <\/strong><\/p>\n\n\n\n<p>Multiple symptoms in multiple systems, a condition that\u2019s\ndifficult to diagnose, dietary treatment \u2013 these probably sound familiar to\nanyone with celiac disease. And it\u2019s possible there is a connection. DAO activity increases progressively from\nthe duodenum to the ileum and is located mainly in the intestinal villi. What\nis the effect when the villi become damaged from celiac disease?<\/p>\n\n\n\n<p>Studies showing lessened DAO enzyme concentrations in untreated celiac patients vs those on a gluten-free diet could be an indicator that there is a relationship to be explored.\u00a0Other <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/2511229\/\" target=\"_blank\" rel=\"noreferrer noopener\" aria-label=\"connections (opens in a new tab)\">connections<\/a> to IBS and non-celiac gluten\/wheat sensitivity (NCGWS) have been established. But studies of histamine intolerance are relatively new. We have much to learn and many connections to make.<\/p>\n\n\n\n<p>In the meantime,\nif you suspect that histamine intolerance good be causing your allergy-like\nsymptoms, keep a food\/symptom diary. This will give you a written history to\nshare with your physician. Don\u2019t be afraid to ask whether they have considered histamine\nintolerance. You are a valuable part of your medical team. <\/p>\n\n\n\n<p>Together with\nyour doctor, you may develop a diagnostic plan that includes some of the\nfollowing: skin-prick test; histamine elimination diet; analysis of blood,\nurine, and stool samples. Once a diagnosis is established, dietary change can\neliminate most or all of the symptoms.<\/p>\n\n\n\n<p>While a dietary\nchange may not be your preference, fewer symptoms will bring you relief. And\nrelief is what most of us are looking for even if what we have is not exactly\nan allergy.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Even though your nose is running, your stomach churning, and your skin itching, you may be experiencing something that\u2019s not exactly an allergy. It could be histamine intolerance. Histamine Intolerance Histamine intolerance, also known as enteral histaminosis, is a disorder that arises because of a body\u2019s inability to degrade histamine due to diminished diamine oxidase &hellip; <a href=\"https:\/\/www.cooking2thrive.com\/blog\/not-exactly-an-allergy\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;Not Exactly an Allergy&#8221;<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[3,4],"tags":[3172,253,3168,3170,3173,3169,3171],"_links":{"self":[{"href":"https:\/\/www.cooking2thrive.com\/blog\/wp-json\/wp\/v2\/posts\/4737"}],"collection":[{"href":"https:\/\/www.cooking2thrive.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.cooking2thrive.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.cooking2thrive.com\/blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.cooking2thrive.com\/blog\/wp-json\/wp\/v2\/comments?post=4737"}],"version-history":[{"count":3,"href":"https:\/\/www.cooking2thrive.com\/blog\/wp-json\/wp\/v2\/posts\/4737\/revisions"}],"predecessor-version":[{"id":4741,"href":"https:\/\/www.cooking2thrive.com\/blog\/wp-json\/wp\/v2\/posts\/4737\/revisions\/4741"}],"wp:attachment":[{"href":"https:\/\/www.cooking2thrive.com\/blog\/wp-json\/wp\/v2\/media?parent=4737"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.cooking2thrive.com\/blog\/wp-json\/wp\/v2\/categories?post=4737"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.cooking2thrive.com\/blog\/wp-json\/wp\/v2\/tags?post=4737"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}